Branzi studied architecture and design in Florence. He founded Archizoom Associati with Paolo Deganello among others. In 1973, he opened his own studio in Milan and exhibited with Studio Alchimia in the early 80’s. In 1977, he organized the famous exhibition ‘Il Disegno italiano degli anni 50’ with Michele De Lucchi. From 1983 to 1987, he was editor of Modo and president of Domus. Branzi designed furniture for Memphis and Zanotta among others.